Stochasticity report — design A

Generated 2026-07-03T07:31:06.561457+00:00. Design root output/calibration_runs/20260703_0711_postfix_stoch/design_A_geography_free. Plan docs/calibration_plan_stochasticity_2026-05.md.

Headline

Result. \(r^\star = \) 9 is the smallest replicate count for which every analysed output satisfies the sustained hybrid MCSE criterion across all 10 parameter sets. The criterion is \(\mathrm{MCSE}_{\mathrm{abs}} < 0.5\) percentage points or \(\mathrm{MCSE}_{\mathrm{rel}} < 5\%\). The diagnostic sweep was run to \(R=20\), so the endpoint provides a margin beyond the observed sufficiency threshold.

Definition. The Monte Carlo standard error (MCSE) is the standard error of the replicate mean. For \(r\) independent seeds, \(\mathrm{MCSE}(r)=s(r)/\sqrt{r}\), where \(s(r)\) is the running sample standard deviation. The report evaluates both absolute MCSE (percentage points) and relative MCSE (absolute MCSE divided by the final mean magnitude). The mathematical definition and sustained-threshold rule are given in the Methodology section.

Recommendations

Recommendation: minimum \(R\ge 9\); guarded calibration budget \(R=10\)–\(15\) seeds per parameter point. The empirical MCSE sufficiency threshold is \(r^\star=9\). The current diagnostic sweep used \(R=20\), which is a validation margin rather than a necessary calibration cost. The output that drives \(r^\star\) is STPM_SexAge_2011-2016_F_65-74 (slowest to satisfy the hybrid criterion). At the audited endpoint \(r=R=20\), the largest residual MCSE is on STPM_IMD_2014-2016_q1 (absolute MCSE 0.48pp, relative MCSE 23.9%).

Family-level diagnostics at \(r=R=20\):

Interpretation for calibration:

  1. The observed \(r^\star\) is an empirical sufficiency threshold for this design, output set, and synthetic population. Once \(r\) is near this value, additional seeds primarily reduce the standard error at the Monte-Carlo rate \(r^{-1/2}\); they should not systematically shift the running mean.
  2. The hybrid criterion is applied per design point: a cell is adequately estimated when \(\mathrm{MCSE}_{\mathrm{abs}} < 0.5\)pp or \(\mathrm{MCSE}_{\mathrm{rel}} < 5\%\). This follows the absolute/relative tolerance logic recommended for small means in simulation studies.
  3. In downstream calibration, include simulator uncertainty by adding the estimated \(\mathrm{MCSE}^2\) to the corresponding target variance term in the loss or implausibility calculation.

Target-aligned endpoint panels

These figures use the same canonical-cell arrangement as the baseline post-processing plots. Each panel reports the stochasticity sweep endpoint: blue bars are the external targets with their sampling uncertainty (\(\pm 1\) SE); each coloured orange mark is one parameter set's seed mean \(\bar{x}_d(R)=\tfrac{1}{R}\sum_{s=1}^{R} x_{d,s,o}\) at \(R=20\), so there are \(M=10\) marks per cell. The thick horizontal orange bar is the median across the \(M\) parameter sets; the thin vertical orange whisker is the across-set range. Marks reflect parameter dispersion under the prior, not Monte Carlo noise within a single point estimate (that is the MCSE diagnostic below). These panels are visual context for target alignment; the seed-budget decision is set by the MCSE analysis in the per-output section.

STPM HSE quit-rate targets
STS quit-attempt constraints
Quit-attempt survival checkpoints

Per-output panels

Cards are grouped by output family (STPM, STS, survival) and ordered within each family by \(r^{\star}_o\) descending then endpoint absolute MCSE descending, matching the Per-output summary table. Top sub-panel: running mean (as percent) across replicate seeds. After convergence, extra seeds narrow uncertainty but should not systematically shift the mean. Black dashed line is the calibration target where defined, shown for visual context. Bottom sub-panel: absolute MCSE (\(\mathrm{MCSE}_{\mathrm{abs}} = s/\sqrt{r}\), in percentage points) — should drop below the red dashed threshold (\(0.5\)pp) or the coloured tick on the right margin (the relative threshold projected onto the same scale). Each coloured line is one parameter set. The three survival checkpoints are summarised in a single combined card.

STPM smoking-prevalence

STPM_SexAge_2011-2016_F_65-74r*ₒ = 9
STPM_SexAge_2011-2016_F_65-74
STPM_IMD_2014-2016_q1r*ₒ = 8
STPM_IMD_2014-2016_q1
STPM_SexAge_2011-2016_M_65-74r*ₒ = 8
STPM_SexAge_2011-2016_M_65-74
STPM_IMD_2011-2013_q2r*ₒ = 6
STPM_IMD_2011-2013_q2
STPM_IMD_2011-2013_q1r*ₒ = 5
STPM_IMD_2011-2013_q1
STPM_IMD_2014-2016_q4r*ₒ = 5
STPM_IMD_2014-2016_q4
STPM_IMD_2011-2013_q3r*ₒ = 4
STPM_IMD_2011-2013_q3
STPM_IMD_2014-2016_q2r*ₒ = 3
STPM_IMD_2014-2016_q2
STPM_IMD_2014-2016_q3r*ₒ = 3
STPM_IMD_2014-2016_q3
STPM_SexAge_2011-2016_F_25-44r*ₒ = 3
STPM_SexAge_2011-2016_F_25-44
STPM_SexAge_2011-2016_F_45-64r*ₒ = 3
STPM_SexAge_2011-2016_F_45-64
STPM_SexAge_2011-2016_M_25-44r*ₒ = 3
STPM_SexAge_2011-2016_M_25-44
STPM_IMD_2011-2013_q4r*ₒ = 2
STPM_IMD_2011-2013_q4
STPM_IMD_2014-2016_q5r*ₒ = 2
STPM_IMD_2014-2016_q5
STPM_IMD_2011-2013_q5r*ₒ = 2
STPM_IMD_2011-2013_q5
STPM_SexAge_2011-2016_M_45-64r*ₒ = 2
STPM_SexAge_2011-2016_M_45-64

STS quit-attempt

STS_SexAge_2011-2016_M_65-74r*ₒ = 4
STS_SexAge_2011-2016_M_65-74
STS_SexAge_2011-2016_F_65-74r*ₒ = 4
STS_SexAge_2011-2016_F_65-74
STS_IMD_2011-2013_q2r*ₒ = 4
STS_IMD_2011-2013_q2
STS_IMD_2011-2013_q1r*ₒ = 3
STS_IMD_2011-2013_q1
STS_IMD_2014-2016_q1r*ₒ = 3
STS_IMD_2014-2016_q1
STS_IMD_2011-2013_q3r*ₒ = 3
STS_IMD_2011-2013_q3
STS_IMD_2014-2016_q2r*ₒ = 2
STS_IMD_2014-2016_q2
STS_IMD_2014-2016_q5r*ₒ = 2
STS_IMD_2014-2016_q5
STS_IMD_2014-2016_q3r*ₒ = 2
STS_IMD_2014-2016_q3
STS_IMD_2011-2013_q4r*ₒ = 2
STS_IMD_2011-2013_q4
STS_IMD_2014-2016_q4r*ₒ = 2
STS_IMD_2014-2016_q4
STS_SexAge_2011-2016_F_45-64r*ₒ = 2
STS_SexAge_2011-2016_F_45-64
STS_SexAge_2011-2016_F_25-44r*ₒ = 2
STS_SexAge_2011-2016_F_25-44
STS_IMD_2011-2013_q5r*ₒ = 2
STS_IMD_2011-2013_q5
STS_SexAge_2011-2016_M_45-64r*ₒ = 2
STS_SexAge_2011-2016_M_45-64
STS_SexAge_2011-2016_M_25-44r*ₒ = 2
STS_SexAge_2011-2016_M_25-44

Quit-attempt survival

SURVIVAL months 3 / 6 / 12 (combined)worst r*ₒ = 2
SURVIVAL combined

Top: per-set seed-mean survival polylines through the 3-, 6-, 12-month checkpoints, against the Jackson envelope and placebo reference. Bottom: worst-of-three-checkpoints absolute MCSE per parameter set as a function of replicate count r. The single combined card replaces the previous three per-month cards.

Per-output summary

Outputs are grouped by family and ordered with the most restrictive cells first (largest \(r^{\star}_o\), then largest endpoint absolute MCSE). The endpoint adequacy column reports the design-level routes through the hybrid criterion at \(r=R\): both criteria, absolute criterion only, or relative criterion only.

STPM smoking-prevalence

output and cellr*oworst MCSE at Rendpoint adequacyinterpretation
STPM_SexAge_2011-2016_F_65-74
2011-2016, Female 65-74
90.40pp
22.2% relative
adequate
4 both, 6 absolute only
sustained from r=9; drives the design-level r*; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2014-2016_q1
2014-2016, IMD q1
80.48pp
23.9% relative
adequate
6 both, 4 absolute only
sustained from r=8; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_SexAge_2011-2016_M_65-74
2011-2016, Male 65-74
80.48pp
37.9% relative
adequate
4 both, 6 absolute only
sustained from r=8; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2011-2013_q2
2011-2013, IMD q2
60.41pp
14.5% relative
adequate
6 both, 4 absolute only
sustained from r=6; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2011-2013_q1
2011-2013, IMD q1
50.40pp
26.6% relative
adequate
5 both, 5 absolute only
sustained from r=5; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2014-2016_q4
2014-2016, IMD q4
50.25pp
15.8% relative
adequate
6 both, 4 absolute only
sustained from r=5; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2011-2013_q3
2011-2013, IMD q3
40.29pp
15.2% relative
adequate
4 both, 6 absolute only
sustained from r=4; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2014-2016_q2
2014-2016, IMD q2
30.32pp
15.5% relative
adequate
6 both, 4 absolute only
sustained from r=3; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2014-2016_q3
2014-2016, IMD q3
30.28pp
17.7% relative
adequate
8 both, 2 absolute only
sustained from r=3; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_SexAge_2011-2016_F_25-44
2011-2016, Female 25-44
30.22pp
11.9% relative
adequate
8 both, 2 absolute only
sustained from r=3; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_SexAge_2011-2016_F_45-64
2011-2016, Female 45-64
30.22pp
14.6% relative
adequate
7 both, 3 absolute only
sustained from r=3; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_SexAge_2011-2016_M_25-44
2011-2016, Male 25-44
30.20pp
8.6% relative
adequate
9 both, 1 absolute only
sustained from r=3; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2011-2013_q4
2011-2013, IMD q4
20.31pp
14.4% relative
adequate
7 both, 3 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2014-2016_q5
2014-2016, IMD q5
20.30pp
14.4% relative
adequate
7 both, 3 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_IMD_2011-2013_q5
2011-2013, IMD q5
20.27pp
14.3% relative
adequate
7 both, 3 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient
STPM_SexAge_2011-2016_M_45-64
2011-2016, Male 45-64
20.15pp
18.2% relative
adequate
8 both, 2 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient

STS quit-attempt

output and cellr*oworst MCSE at Rendpoint adequacyinterpretation
STS_SexAge_2011-2016_M_65-74
2011-2016, Male 65-74
40.75pp
2.6% relative
adequate
4 both, 6 relative only
sustained from r=4; absolute maximum is above the 0.5pp reference but relative precision is sufficient
STS_SexAge_2011-2016_F_65-74
2011-2016, Female 65-74
40.62pp
3.0% relative
adequate
5 both, 5 relative only
sustained from r=4; absolute maximum is above the 0.5pp reference but relative precision is sufficient
STS_IMD_2011-2013_q2
2011-2013, IMD q2
40.43pp
1.8% relative
adequate
10 both
sustained from r=4; both worst-case criteria are below their reference thresholds
STS_IMD_2011-2013_q1
2011-2013, IMD q1
30.48pp
1.5% relative
adequate
10 both
sustained from r=3; both worst-case criteria are below their reference thresholds
STS_IMD_2014-2016_q1
2014-2016, IMD q1
30.46pp
1.5% relative
adequate
10 both
sustained from r=3; both worst-case criteria are below their reference thresholds
STS_IMD_2011-2013_q3
2011-2013, IMD q3
30.35pp
1.3% relative
adequate
10 both
sustained from r=3; both worst-case criteria are below their reference thresholds
STS_IMD_2014-2016_q2
2014-2016, IMD q2
20.42pp
1.5% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_IMD_2014-2016_q5
2014-2016, IMD q5
20.39pp
1.1% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_IMD_2014-2016_q3
2014-2016, IMD q3
20.38pp
1.0% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_IMD_2011-2013_q4
2011-2013, IMD q4
20.36pp
1.2% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_IMD_2014-2016_q4
2014-2016, IMD q4
20.32pp
0.8% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_SexAge_2011-2016_F_45-64
2011-2016, Female 45-64
20.30pp
1.4% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_SexAge_2011-2016_F_25-44
2011-2016, Female 25-44
20.28pp
1.1% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_IMD_2011-2013_q5
2011-2013, IMD q5
20.28pp
1.5% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_SexAge_2011-2016_M_45-64
2011-2016, Male 45-64
20.25pp
1.4% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds
STS_SexAge_2011-2016_M_25-44
2011-2016, Male 25-44
20.25pp
0.7% relative
adequate
10 both
sustained from r=2; both worst-case criteria are below their reference thresholds

Quit-attempt survival

output and cellr*oworst MCSE at Rendpoint adequacyinterpretation
SURVIVAL_month_6
month_6
20.06pp
16.4% relative
adequate
5 both, 3 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient
SURVIVAL_month_3
month_3
20.06pp
7.1% relative
adequate
7 both, 2 absolute only
sustained from r=2; relative maximum is denominator-sensitive; absolute precision is sufficient
SURVIVAL_month_12
month_12
20.04pp
4.7% relative
adequate
5 both
sustained from r=2; both worst-case criteria are below their reference thresholds

Background

The ABM is stochastic: repeated runs at the same parameter point yield slightly different outputs. The calibration target is the expectation of each output under the simulator, estimated here by averaging over replicate seeds. MCSE quantifies the remaining simulation error in that mean estimate. This report estimates the replicate count at which that simulation error is small enough relative to predefined absolute and relative tolerances.

This is purely about simulator precision, not about matching calibration targets (a separate question). Target lines in the panels above are shown for context only.

Vocabulary

Methodology

Let \(x_{d,s,o}\) be the value of output \(o\) from the run at parameter point \(d\) with seed \(s\). For each \((d,o)\) we form the running mean and running sample variance over the first \(r\) seeds (\(2 \le r \le R\)):

$$\bar{x}_d(r) \;=\; \frac{1}{r}\sum_{s=1}^{r} x_{d,s,o},\qquad s^{2}_d(r) \;=\; \frac{1}{r-1}\sum_{s=1}^{r}\bigl(x_{d,s,o}-\bar{x}_d(r)\bigr)^{2}.$$

The standard error of the mean estimator from \(r\) replicates — the absolute Monte-Carlo standard error — is

$$\mathrm{MCSE}_{\mathrm{abs}}(r;\,d,o) \;=\; \sqrt{s^{2}_d(r)/r}.$$

It is in the same units as the output (here, probability; reported in percentage points). Dividing by the final mean's absolute value gives the scale-free relative version,

$$\mathrm{MCSE}_{\mathrm{rel}}(r;\,d,o) \;=\; \frac{\mathrm{MCSE}_{\mathrm{abs}}(r;\,d,o)}{|\bar{x}_d(R)|}.$$

Both decay like \(1/\sqrt{r}\). Each is the right metric in some regime: relative MCSE is interpretable when the mean is well away from zero, but it explodes spuriously when the mean is small (a sub-percentage-point wobble around a 2% prevalence is 25% in relative terms but irrelevant for calibration). We therefore use a hybrid pass criterion: an output passes at replicate count \(r\) for parameter set \(d\) if

$$\mathrm{MCSE}_{\mathrm{abs}}(r;d,o) \;<\; \tau_{\mathrm{abs}} \quad\text{or}\quad \mathrm{MCSE}_{\mathrm{rel}}(r;d,o) \;<\; \tau_{\mathrm{rel}}.$$

Equivalently, the output's headroom

$$h(r;\,d,o) \;=\; \min\!\Bigl(\tfrac{\mathrm{MCSE}_{\mathrm{abs}}(r;d,o)}{\tau_{\mathrm{abs}}},\;\tfrac{\mathrm{MCSE}_{\mathrm{rel}}(r;d,o)}{\tau_{\mathrm{rel}}}\Bigr) \;<\; 1.$$

For each output we then take the worst case across parameter points, \(h^{\max}_o(r) = \max_d h(r;d,o)\), and define

$$r^{\star}_o \;=\; \min\!\bigl\{\,r\,:\;h^{\max}_o(r')<1 \;\;\forall\;r'\ge r\,\bigr\},\qquad r^{\star} \;=\; \max_o\, r^{\star}_o,$$

with thresholds \(\tau_{\mathrm{abs}}=0.5\)pp and \(\tau_{\mathrm{rel}}=5\%\). \(r^{\star}_o\) is the smallest replicate budget at which output \(o\) becomes precise enough on at least one of the two scales and stays that way; \(r^{\star}\) is the worst over outputs and is the operational answer.

The "all-subsequent-stay-below" rule and worst-output aggregation follow JASSS Lee et al. (2015, §2.6, §2.11). The hybrid abs/rel pass criterion follows their §2.7 recommendation. MCSE \(=s/\sqrt{r}\) is the standard sizing quantity used in simulation studies (Flegal, Haran & Jones 2008 Statistical Science; Koehler et al. 2009).

Caveat. At small \(r\) (2–4) the running variance \(s^{2}(r)\) is noisy, so MCSE curves jitter near the left edge of each panel. The all-subsequent-stay-below rule plus \(R\ge 20\) anchoring the right end means this does not affect the headline number.

Sampling design

design_nameA
M (parameter sets)10
R (replicate seeds)20
D_total / D_sampled / D_frozen40 / 40 / 0
samplerscipy.stats.qmc.Sobol (scipy 1.17.1)
sampler argsd=40, scramble=True, seed=20260501; n_drawn=10
trunc_sd_default4.0
git_sha8c21082e72dc92c8ba5f139e777d104887f0354e
hostnamecrunch-Custom-TRX50
priors_csvoutput/calibration_runs/20260703_0711_postfix_stoch/priors_v1_designA.csv
priors sha25623ad0608a92a4ac30f733d17d078163905fb6508fefab672e105a6329a10c92d
parameter_design sha256492c84000a54178e83dff1977450bf9635da9a9dfb4e1f2fc3bfd27d674a495e

Source files for priors

No source-file metadata found.

Parameter sets

The 10 parameter sets vary 40 of 40 model parameters; the remaining 0 are held constant across all sets in this design.

Varying parameters (one column per parameter set)

parameterdesign_0001design_0002design_0003design_0004design_0005design_0006design_0007design_0008design_0009design_0010
attempt.oSocialHousing.beta0.2645170.0864516-0.06867060.1116890.202892-0.358294-0.007089390.6450410.4053590.0287785
attempt.oPrevalenceOfSmokingInGeographicLocality.beta3.035041.029912.903870.2596011.86007-0.3214584.905961.520482.531540.700097
attempt.oReceiptGPAdvice.beta0.1148260.005396340.1632190.0347215-0.0591980.08727770.07871220.2000550.05315290.280932
attempt.oNumberOfSmokersInSocialNetwork.beta0.0640842-0.06732650.13361-0.00557423-0.0137060.0689761-0.09673990.02082040.0873259-0.0281767
attempt.cSelfEfficacy.beta0.277690.5173890.2909110.04520420.161670.3583840.4018860.2109560.5617370.234256
attempt.mIntentionToQuit.beta0.1907710.2318580.2165340.1775780.1978620.248870.2090280.1655870.1697510.211881
attempt.mExpenditure.beta0.00389422-0.0004692050.001579330.0002300690.002359390.0008017990.00314079-0.003070.002597340.00127248
attempt.mEnjoymentOfSmoking.beta-0.311669-0.0787119-0.192547-0.501652-0.107383-0.333104-0.2149270.0802652-0.146976-0.384066
attempt.mUseOfNRT.beta0.4550160.1861520.3125930.3221270.2508750.3851860.5039140.1457790.2590310.371147
attempt.mNumberOfRecentQuitAttempts.beta0.3321430.325610.2304870.4158160.3063350.3439510.3820860.2835020.3849820.255119
attempt.mAgeGroup30To44.beta-0.382686-0.00495928-0.164043-0.187438-0.124537-0.239194-0.287864-0.0679786-0.0432628-0.330594
attempt.mAgeGroup45To64.beta-0.237958-0.0244811-0.121936-0.320746-0.394916-0.17034-0.103626-0.283603-0.2159220.0606901
attempt.mAgeGroup65Plus.beta-0.0439635-0.2473350.127875-0.1069240.0914059-0.203584-0.0686287-0.503428-0.1613450.0308683
maintenance.cAlcoholConsumptionGroupHigherRisk.beta0.45046-0.398930.6913630.147259-0.04471140.3805610.2671520.5762050.1940550.590447
maintenance.cAlcoholConsumptionGroupIncreasingRisk.beta-0.03803410.2849650.369435-0.186572-0.2317290.5024170.1271510.07598570.29963-0.106504
maintenance.cAlcoholConsumptionGroupLowerRisk.beta0.30232-0.05244060.193772-0.0904439-0.4273320.1406020.07779940.395166-0.199310.105237
maintenance.cECigUse.beta-0.4320811.570660.7364870.1095340.3274090.5294481.05433-0.08280030.7734280.146689
maintenance.cPrescriptionNRT.beta0.2130720.481170.1444150.3156860.2774620.2050640.3883560.2455810.3400880.0628745
maintenance.cCigConsumptionPreQuit.beta-0.0546405-0.0281759-0.0192126-0.0378273-0.00843118-0.0321777-0.0450396-0.0249191-0.00379774-0.0310964
maintenance.cVareniclineUse.beta0.803490.3514811.388760.641870.7358520.5146440.9384630.7156140.9771330.592863
maintenance.cAgeGroup30To44.beta0.339380.03615890.820809-0.168860.2430310.1284540.529433-0.002334240.3052220.192023
maintenance.cAgeGroup45To64.beta0.352485-0.138855-0.0531030.216560.441629-0.4819430.08761070.174286-0.2337590.729717
maintenance.cAgeGroup65Plus.beta0.1394160.854055-0.2324660.248097-0.06058350.3454650.002225470.5532210.1148050.51958
maintenance.cMentalHealthCondition.beta0.161461-0.3170240.058017-0.198408-0.135707-0.0220811-0.5558920.409805-0.0762799-0.0536373
maintenance.cCigAddictStrength.beta-0.16985-0.0973439-0.2618730.00661724-0.084431-0.298748-0.143744-0.186874-0.381558-0.0589111
maintenance.cUseOfBehaviouralSupport.beta-0.01899290.2794340.3574610.1779670.4938360.1251940.06129810.207616-0.1118370.307754
maintenance.cEducationalLevelBelowDegree.beta-0.4021620.677467-0.291289-0.0804261-0.2501-0.0647146-0.7879740.04354990.196758-0.49664
maintenance.cEducationalLevelDegreeOrHigher.beta-0.8987330.1320450.0386188-0.190380.382393-0.4564-0.349186-0.112028-0.4161920.477763
maintenance.cNumberOfRecentQuitAttempts.beta-0.0760359-0.152605-0.017198-0.160948-0.0991428-0.127760.119524-0.207347-0.116094-0.0879206
maintenance.oSocialHousing.beta-0.4080050.00574431-0.269838-0.718956-0.444246-0.0796322-0.233356-0.625086-0.210589-0.531461
maintenance.oNumberOfSmokersInSocialNetwork.beta-0.0814476-0.0442032-0.122499-0.0110687-0.09708070.062659-0.0583305-0.0304929-0.1126040.00969778
maintenance.oPrevalenceOfSmokingInGeographicLocality.beta7.347060.03755260.967968-8.34574.4251-1.400462.49657-4.26952-5.20011.32347
maintenance.oSEP.beta0.242345-0.372691-0.0691682-0.117953-0.1769440.018598-0.2586790.1050730.185517-0.921495
maintenance.cCytisineUse.beta0.7457840.8888150.9966660.3330821.22340.4647580.597260.8366391.339210.563475
maintenance.mNonSmokerSelfIdentity.beta-0.4503051.208111.507380.464820.834876-0.2531620.3801442.227011.13563-1.17196
attempt.bias-4.32455-3.63033-3.77627-4.16525-2.57077-4.79072-4.08072-3.88056-4.05405-3.96167
maintenance.bias-2.187130.207909-0.9938011.60446-0.335476-1.632630.593173-0.667698-1.43371-0.0885009
lambda0.03468930.03691730.03009010.04219090.04633550.02484290.03914250.03244920.04450170.0321848
alpha1.424631.070611.335610.06882771.199790.8102111.740490.928661.276290.638929
beta0.4821350.5455330.3471870.5993260.7088420.3614070.5310270.4344350.5781780.472416

Parameters (priors v1)

40 parameters; 0 frozen (yellow rows). The mean and sd columns define the truncated normal prior used by Sobol inverse-CDF sampling.

Prior distributions and realised parameter sets

Each panel shows the truncated prior density for one parameter. Coloured vertical marks show the realised values for the parameter sets in this design; colours follow the parameter-set order used in the output plots.

12345678910
attempt.oSocialHousing.beta prior positions

attempt.oSocialHousing.beta
sampled range -0.3583 to 0.645

attempt.oPrevalenceOfSmokingInGeographicLocality.beta prior positions

attempt.oPrevalenceOfSmokingInGeographicLocality.beta
sampled range -0.3215 to 4.906

attempt.oReceiptGPAdvice.beta prior positions

attempt.oReceiptGPAdvice.beta
sampled range -0.0592 to 0.2809

attempt.oNumberOfSmokersInSocialNetwork.beta prior positions

attempt.oNumberOfSmokersInSocialNetwork.beta
sampled range -0.09674 to 0.1336

attempt.cSelfEfficacy.beta prior positions

attempt.cSelfEfficacy.beta
sampled range 0.0452 to 0.5617

attempt.mIntentionToQuit.beta prior positions

attempt.mIntentionToQuit.beta
sampled range 0.1656 to 0.2489

attempt.mExpenditure.beta prior positions

attempt.mExpenditure.beta
sampled range -0.00307 to 0.003894

attempt.mEnjoymentOfSmoking.beta prior positions

attempt.mEnjoymentOfSmoking.beta
sampled range -0.5017 to 0.08027

attempt.mUseOfNRT.beta prior positions

attempt.mUseOfNRT.beta
sampled range 0.1458 to 0.5039

attempt.mNumberOfRecentQuitAttempts.beta prior positions

attempt.mNumberOfRecentQuitAttempts.beta
sampled range 0.2305 to 0.4158

attempt.mAgeGroup30To44.beta prior positions

attempt.mAgeGroup30To44.beta
sampled range -0.3827 to -0.004959

attempt.mAgeGroup45To64.beta prior positions

attempt.mAgeGroup45To64.beta
sampled range -0.3949 to 0.06069

attempt.mAgeGroup65Plus.beta prior positions

attempt.mAgeGroup65Plus.beta
sampled range -0.5034 to 0.1279

maintenance.cAlcoholConsumptionGroupHigherRisk.beta prior positions

maintenance.cAlcoholConsumptionGroupHigherRisk.beta
sampled range -0.3989 to 0.6914

maintenance.cAlcoholConsumptionGroupIncreasingRisk.beta prior positions

maintenance.cAlcoholConsumptionGroupIncreasingRisk.beta
sampled range -0.2317 to 0.5024

maintenance.cAlcoholConsumptionGroupLowerRisk.beta prior positions

maintenance.cAlcoholConsumptionGroupLowerRisk.beta
sampled range -0.4273 to 0.3952

maintenance.cECigUse.beta prior positions

maintenance.cECigUse.beta
sampled range -0.4321 to 1.571

maintenance.cPrescriptionNRT.beta prior positions

maintenance.cPrescriptionNRT.beta
sampled range 0.06287 to 0.4812

maintenance.cCigConsumptionPreQuit.beta prior positions

maintenance.cCigConsumptionPreQuit.beta
sampled range -0.05464 to -0.003798

maintenance.cVareniclineUse.beta prior positions

maintenance.cVareniclineUse.beta
sampled range 0.3515 to 1.389

maintenance.cAgeGroup30To44.beta prior positions

maintenance.cAgeGroup30To44.beta
sampled range -0.1689 to 0.8208

maintenance.cAgeGroup45To64.beta prior positions

maintenance.cAgeGroup45To64.beta
sampled range -0.4819 to 0.7297

maintenance.cAgeGroup65Plus.beta prior positions

maintenance.cAgeGroup65Plus.beta
sampled range -0.2325 to 0.8541

maintenance.cMentalHealthCondition.beta prior positions

maintenance.cMentalHealthCondition.beta
sampled range -0.5559 to 0.4098

maintenance.cCigAddictStrength.beta prior positions

maintenance.cCigAddictStrength.beta
sampled range -0.3816 to 0.006617

maintenance.cUseOfBehaviouralSupport.beta prior positions

maintenance.cUseOfBehaviouralSupport.beta
sampled range -0.1118 to 0.4938

maintenance.cEducationalLevelBelowDegree.beta prior positions

maintenance.cEducationalLevelBelowDegree.beta
sampled range -0.788 to 0.6775

maintenance.cEducationalLevelDegreeOrHigher.beta prior positions

maintenance.cEducationalLevelDegreeOrHigher.beta
sampled range -0.8987 to 0.4778

maintenance.cNumberOfRecentQuitAttempts.beta prior positions

maintenance.cNumberOfRecentQuitAttempts.beta
sampled range -0.2073 to 0.1195

maintenance.oSocialHousing.beta prior positions

maintenance.oSocialHousing.beta
sampled range -0.719 to 0.005744

maintenance.oNumberOfSmokersInSocialNetwork.beta prior positions

maintenance.oNumberOfSmokersInSocialNetwork.beta
sampled range -0.1225 to 0.06266

maintenance.oPrevalenceOfSmokingInGeographicLocality.beta prior positions

maintenance.oPrevalenceOfSmokingInGeographicLocality.beta
sampled range -8.346 to 7.347

maintenance.oSEP.beta prior positions

maintenance.oSEP.beta
sampled range -0.9215 to 0.2423

maintenance.cCytisineUse.beta prior positions

maintenance.cCytisineUse.beta
sampled range 0.3331 to 1.339

maintenance.mNonSmokerSelfIdentity.beta prior positions

maintenance.mNonSmokerSelfIdentity.beta
sampled range -1.172 to 2.227

attempt.bias prior positions

attempt.bias
sampled range -4.791 to -2.571

maintenance.bias prior positions

maintenance.bias
sampled range -2.187 to 1.604

lambda prior positions

lambda
sampled range 0.02484 to 0.04634

alpha prior positions

alpha
sampled range 0.06883 to 1.74

beta prior positions

beta
sampled range 0.3472 to 0.7088

namekindmeansdsupporttransformfrozensource_term
attempt.oSocialHousing.betasem_beta_attempt0.096230.2065-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoSocialHousing
attempt.oPrevalenceOfSmokingInGeographicLocality.betasem_beta_attempt1.8231.624-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoPrevalenceOfSmokingInGeographicLocality
attempt.oReceiptGPAdvice.betasem_beta_attempt0.079070.1045-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoReceiptGPAdvice
attempt.oNumberOfSmokersInSocialNetwork.betasem_beta_attempt0.012640.07701-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoNumberOfSmokersInSocialNetwork
attempt.cSelfEfficacy.betasem_beta_attempt0.28230.1664-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecSelfEfficacy
attempt.mIntentionToQuit.betasem_beta_attempt0.20190.02869-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemIntentionToQuit
attempt.mExpenditure.betasem_beta_attempt0.0014170.002111-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemExpenditure
attempt.mEnjoymentOfSmoking.betasem_beta_attempt-0.20680.1827-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemEnjoymentOfSmoking
attempt.mUseOfNRT.betasem_beta_attempt0.3130.1248-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemUseOfNRT
attempt.mNumberOfRecentQuitAttempts.betasem_beta_attempt0.32810.04781-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemNumberOfRecentQuitAttempts
attempt.mAgeGroup30To44.betasem_beta_attempt-0.17150.1403-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemAgeGroup30To44
attempt.mAgeGroup45To64.betasem_beta_attempt-0.21480.1402-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemAgeGroup45To64
attempt.mAgeGroup65Plus.betasem_beta_attempt-0.1050.1733-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemAgeGroup65Plus
maintenance.cAlcoholConsumptionGroupHigherRisk.betasem_beta_maintenance0.2850.3335-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAlcoholConsumptionGroupHigherRisk
maintenance.cAlcoholConsumptionGroupIncreasingRisk.betasem_beta_maintenance0.11440.2665-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAlcoholConsumptionGroupIncreasingRisk
maintenance.cAlcoholConsumptionGroupLowerRisk.betasem_beta_maintenance0.086320.2333-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAlcoholConsumptionGroupLowerRisk
maintenance.cECigUse.betasem_beta_maintenance0.44510.6396-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecECigUse
maintenance.cPrescriptionNRT.betasem_beta_maintenance0.27590.1025-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecPrescriptionNRT
maintenance.cCigConsumptionPreQuit.betasem_beta_maintenance-0.029570.01417-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecCigConsumptionPreQuit
maintenance.cVareniclineUse.betasem_beta_maintenance0.71590.2062-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecVareniclineUse
maintenance.cAgeGroup30To44.betasem_beta_maintenance0.21720.2795-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAgeGroup30To44
maintenance.cAgeGroup45To64.betasem_beta_maintenance0.097520.276-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAgeGroup45To64
maintenance.cAgeGroup65Plus.betasem_beta_maintenance0.2320.3455-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecAgeGroup65Plus
maintenance.cMentalHealthCondition.betasem_beta_maintenance-0.074340.2881-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecMentalHealthCondition
maintenance.cCigAddictStrength.betasem_beta_maintenance-0.15480.095-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecCigAddictStrength
maintenance.cUseOfBehaviouralSupport.betasem_beta_maintenance0.20380.1911-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecUseOfBehaviouralSupport
maintenance.cEducationalLevelBelowDegree.betasem_beta_maintenance-0.17410.3105-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecEducationalLevelBelowDegree
maintenance.cEducationalLevelDegreeOrHigher.betasem_beta_maintenance-0.12310.3549-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecEducationalLevelDegreeOrHigher
maintenance.cNumberOfRecentQuitAttempts.betasem_beta_maintenance-0.10450.08211-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecNumberOfRecentQuitAttempts
maintenance.oSocialHousing.betasem_beta_maintenance-0.3440.271-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoSocialHousing
maintenance.oNumberOfSmokersInSocialNetwork.betasem_beta_maintenance-0.058020.05013-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoNumberOfSmokersInSocialNetwork
maintenance.oPrevalenceOfSmokingInGeographicLocality.betasem_beta_maintenance0.3374.559-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoPrevalenceOfSmokingInGeographicLocality
maintenance.oSEP.betasem_beta_maintenance-0.10390.2156-inf – infidentity; prior SD scaled x2 for sensitivity runFalseoSEP
maintenance.cCytisineUse.betasem_beta_maintenance0.7930.292-inf – infidentity; prior SD scaled x2 for sensitivity runFalsecCytisineUse
maintenance.mNonSmokerSelfIdentity.betasem_beta_maintenance0.71780.9226-inf – infidentity; prior SD scaled x2 for sensitivity runFalsemNonSmokerSelfIdentity
attempt.biasbias_attempt_transformed-3.9950.4567-inf – inflogit(1 - (1 - sigma(b_6))^(1/6)); b_6=-2.156946, p_6=0.103684, p_1=0.018078, J(db_1/db_6)=0.955879, SE(b_6)=0.238892; prior SD scaled x2 for sensitivity runFalse(Intercept: geo prevalence = 0) [analytic 6mo->1mo transform]
maintenance.biasbias_maintenance_raw-0.45631.307-inf – infidentity (no time-scale transformation; deferred); prior SD scaled x2 for sensitivity runFalse(Intercept: geo prevalence = 0)
lambdafeedback0.03680.0068360.0 – infidentity; prior SD scaled x2 for sensitivity runFalseCigAddictStrength b (Hazel's analysis, R nls)
alphafeedback1.1310.3241-inf – infidentity; prior SD scaled x2 for sensitivity runFalseNonSmokerSelfIdentity alpha (Hazel's analysis, R nls)
betafeedback0.50.1242-inf – infidentity; prior SD scaled x2 for sensitivity runFalseNonSmokerSelfIdentity beta (Hazel's analysis, R nls)

Outputs

35 aggregate outputs per run: 16 STPM smoking-prevalence cells (10 IMD: q1–q5 × {2011-2013, 2014-2016}; 6 sex×age: {F,M} × {25-44, 45-64, 65-74} for the combined 2011-2016 period) + 16 STS quit-attempt cells on the same 10+6 strata (sex×age cells inverse-variance-combined from the two HSE periods, since the target file does not publish 2011-2016 directly) + 3 survival checkpoints (months 3, 6, 12).

output_idfamilycelltarget / definition
STPM_IMD_2011-2013_q1STPM smoking-prevalence cellIMD 2011-2013 q1T_002: p=0.1154 var=2.65e-05
STPM_IMD_2011-2013_q2STPM smoking-prevalence cellIMD 2011-2013 q2T_005: p=0.1063 var=1.47e-05
STPM_IMD_2011-2013_q3STPM smoking-prevalence cellIMD 2011-2013 q3T_008: p=0.0899 var=1.12e-05
STPM_IMD_2011-2013_q4STPM smoking-prevalence cellIMD 2011-2013 q4T_011: p=0.0793 var=9.59e-06
STPM_IMD_2011-2013_q5STPM smoking-prevalence cellIMD 2011-2013 q5T_014: p=0.0580 var=7.29e-06
STPM_IMD_2014-2016_q1STPM smoking-prevalence cellIMD 2014-2016 q1T_027: p=0.1253 var=5.72e-05
STPM_IMD_2014-2016_q2STPM smoking-prevalence cellIMD 2014-2016 q2T_030: p=0.1121 var=3.33e-05
STPM_IMD_2014-2016_q3STPM smoking-prevalence cellIMD 2014-2016 q3T_033: p=0.0977 var=2.90e-05
STPM_IMD_2014-2016_q4STPM smoking-prevalence cellIMD 2014-2016 q4T_036: p=0.0836 var=2.15e-05
STPM_IMD_2014-2016_q5STPM smoking-prevalence cellIMD 2014-2016 q5T_039: p=0.0619 var=1.70e-05
STPM_SexAge_2011-2016_F_25-44STPM smoking-prevalence cellSexAge 2011-2016 Female 25-44T_017: p=0.0977 var=1.04e-05
STPM_SexAge_2011-2016_F_45-64STPM smoking-prevalence cellSexAge 2011-2016 Female 45-64T_018: p=0.0706 var=1.01e-05
STPM_SexAge_2011-2016_F_65-74STPM smoking-prevalence cellSexAge 2011-2016 Female 65-74T_019: p=0.0687 var=2.38e-05
STPM_SexAge_2011-2016_M_25-44STPM smoking-prevalence cellSexAge 2011-2016 Male 25-44T_022: p=0.0986 var=1.27e-05
STPM_SexAge_2011-2016_M_45-64STPM smoking-prevalence cellSexAge 2011-2016 Male 45-64T_023: p=0.0739 var=1.19e-05
STPM_SexAge_2011-2016_M_65-74STPM smoking-prevalence cellSexAge 2011-2016 Male 65-74T_024: p=0.0643 var=2.54e-05
STS_IMD_2011-2013_q1STS quit-attempt rate cellIMD 2011-2013 q1p=0.4578 var=1.01e-03
STS_IMD_2011-2013_q2STS quit-attempt rate cellIMD 2011-2013 q2p=0.3416 var=1.46e-03
STS_IMD_2011-2013_q3STS quit-attempt rate cellIMD 2011-2013 q3p=0.4440 var=1.79e-03
STS_IMD_2011-2013_q4STS quit-attempt rate cellIMD 2011-2013 q4p=0.4082 var=7.86e-04
STS_IMD_2011-2013_q5STS quit-attempt rate cellIMD 2011-2013 q5p=0.3671 var=2.70e-04
STS_IMD_2014-2016_q1STS quit-attempt rate cellIMD 2014-2016 q1p=0.4052 var=3.08e-04
STS_IMD_2014-2016_q2STS quit-attempt rate cellIMD 2014-2016 q2p=0.3492 var=5.18e-04
STS_IMD_2014-2016_q3STS quit-attempt rate cellIMD 2014-2016 q3p=0.3445 var=4.47e-04
STS_IMD_2014-2016_q4STS quit-attempt rate cellIMD 2014-2016 q4p=0.3288 var=1.89e-04
STS_IMD_2014-2016_q5STS quit-attempt rate cellIMD 2014-2016 q5p=0.3027 var=5.87e-05
STS_SexAge_2011-2016_F_25-44STS quit-attempt rate cellSexAge 2011-2016 Female 25-44p=0.4228 var=2.06e-04
STS_SexAge_2011-2016_F_45-64STS quit-attempt rate cellSexAge 2011-2016 Female 45-64p=0.3351 var=1.96e-04
STS_SexAge_2011-2016_F_65-74STS quit-attempt rate cellSexAge 2011-2016 Female 65-74p=0.2868 var=5.58e-04
STS_SexAge_2011-2016_M_25-44STS quit-attempt rate cellSexAge 2011-2016 Male 25-44p=0.3880 var=2.68e-04
STS_SexAge_2011-2016_M_45-64STS quit-attempt rate cellSexAge 2011-2016 Male 45-64p=0.2815 var=1.39e-04
STS_SexAge_2011-2016_M_65-74STS quit-attempt rate cellSexAge 2011-2016 Male 65-74p=0.2218 var=3.73e-04
SURVIVAL_month_12Survival fraction at month k after attempt initiationmonth_12(Jackson survival envelope; reported but not in r* target set)
SURVIVAL_month_3Survival fraction at month k after attempt initiationmonth_3(Jackson survival envelope; reported but not in r* target set)
SURVIVAL_month_6Survival fraction at month k after attempt initiationmonth_6(Jackson survival envelope; reported but not in r* target set)